Foresite Capital Management IV, LLC — 13F Holdings

2026 Q2  ·  9 Positions

2026 Q2 Portfolio Activity

In 2026 Q2, Foresite Capital Management IV, LLC maintained a portfolio of 9 distinct positions. The most significant new addition was Crinetics Pharmaceuticals, Inc, now representing 1.93% of the total fund value. They heavily accumulated shares in CYTOKINETICS INC, increasing the position by 42.0%. Conversely, Foresite Capital Management IV, LLC completely exited their position in Lyell Immunopharma, Inc..
Position History hover any row below to update
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Foresite Capital Management IV, LLC San Francisco, CA Venture Capital / Crossover Fund AUM $290M
PCA Score Concentration Risk
Risk ENB
Total Positions
9
Quarter
2026 Q2
Top Holding
PHVS (57.0%)
Top 10 Concentration
100.0%
Turnover Rate
23.4%
Sector HHI
0.18
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Showing 1-9 of 9

Foresite Capital Management IV, LLC Full Holdings List — 2026 Q2

Stock History Sector / Type Port % Prev % Rank / Prev Conviction
Freshness
Change % Change Influence Shares Mkt Value Avg Cost Price Held 1st Owned Source Source Date Date Reported
PHVS
Pharvaris N.V.
Healthcare 56.95% 56.94% #1
Prev: #1
7.0
no change no change
P
S
4,778,581 $165,243,331 2021 Q1 13F Filing 2026-06-30 2026-08-14
CYTK
CYTOKINETICS IN...
Healthcare 20.98% 13.99% #2
Prev: #2
8.0
211,400 42.0%
P
S
714,695 $60,884,867 2018 Q4 13F Filing 2026-06-30 2026-08-14
N/A
Eikon Therapeut...
Unknown 8.74% 8.67% #3
Prev: #3
5.5
no change no change
P
S
1,943,682 $25,365,050 13F Filing 2026-06-30 2026-08-14
RLAY
Relay Therapeut...
Healthcare 8.06% 4.20% #4 1
Prev: #5
6.2
250,000 25.0%
P
S
1,250,000 $23,387,500 2020 Q3 13F Filing 2026-06-30 2026-08-14
XENE
Xenon Pharmaceu...
Healthcare 3.33% 3.92% #5 1
Prev: #6
2.8
no change no change
P
S
160,000 $9,657,600 2018 Q3 13F Filing 2026-06-30 2026-08-14
CRNX
Crinetics Pharm...
Healthcare 1.93% #6
Prev: #—
4.3
150,000
NEW
150,000 $5,613,000 2018 Q3 13F Filing 2026-06-30 2026-08-14
MAZE
Maze Therapeuti...
Healthcare 0.00% 1.98%
Sold All 😨
(Was: #8)
0.0
-156,901 -100.0%
CLOSED
$— 2025 Q1 13F Filing 2026-06-30 2026-08-14
ALEC
Alector, Inc.
Healthcare 0.00% 3.53%
Sold All 😨
(Was: #7)
0.0
-3,887,200 -100.0%
CLOSED
$— 2019 Q1 13F Filing 2026-06-30 2026-08-14
LYEL
Lyell Immunopha...
Healthcare 0.00% 6.77%
Sold All 😨
(Was: #4)
0.0
-800,399 -100.0%
CLOSED
$— 2021 Q2 13F Filing 2026-06-30 2026-08-14
Showing 1-9 of 9 holdings

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