PERCEPTIVE ADVISORS LLC reported ISIS PHARMACEUTICALS COM (IONS) in 14 quarterly 13F filings from 2026 Q1 through 2026 Q1. Peak portfolio weight reached 0.74% in 2026 Q1. The latest visible filing shows IONS at 0.74% of the fund.
This page tracks quarterly shares, estimated market value, portfolio weight, filing dates, and disclosure-aligned stock prices directly from SEC EDGAR 13F filings. Older history is available after unlock; the visible window still shows the most recent pattern.
This page is designed to answer the real investor question behind a 13F filing: how meaningful was PERCEPTIVE ADVISORS LLC's position in ISIS PHARMACEUTICALS COM, and how did that conviction change over time? You can read the holding window, peak weight, latest reported size, disclosure timing, and quarter-by-quarter changes without piecing the story together from raw SEC rows.
IONS was reported at 0.74% of portfolio in the most recent visible filing.
Peak weight helps separate a token disclosure from a real conviction holding the fund genuinely cared about.
Longer holding windows often tell a very different story from short-lived tactical trades or one-quarter experiments.
Knowing that a fund owned a stock is useful. Knowing whether it was a 0.20% placeholder or a true high-conviction position is where the signal actually starts.
As of 2026 Q1 — sorted by position size
These are the practical questions this page is built to answer before you even open the full history table.
PERCEPTIVE ADVISORS LLC reported IONS across 1 quarterly 13F filings, from 2026 Q1 through 2026 Q1.
The largest reported portfolio weight for IONS was 0.74% in 2026 Q1.
The most recent filing on this page is 2026 Q1, when PERCEPTIVE ADVISORS LLC reported 504,000 shares, equal to 0.74% of portfolio, with an estimated market value of $37.8M.
The chart compares PERCEPTIVE ADVISORS LLC's quarterly IONS portfolio weight with the stock's indexed share price, so you can see whether the fund was building, trimming, or holding the position as price moved.
Based on 13F filing dates vs. subsequent IONS price moves, PERCEPTIVE ADVISORS LLC correctly timed 4 out of 12 reported position changes (33%). The annualised alpha on IONS relative to SPY over the holding period was +196.2%.