Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Lexicon Pharmaceuticals Inc (LXRX)

147 + Investors. Track Smart Money conviction in LXRX. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +12
Streak
2Q ▲
Buyers last Q
55%

Smart Money Signals — LXRX

Based on 148 hedge funds · latest filing: 2026 Q2 · updated quarterly

📈

Buying streak — 2 quarters in a row

last 6Q
For 2 consecutive quarters, more hedge funds added LXRX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
148 hedge funds hold LXRX right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
🚀

Fast accumulation — +22% more funds vs a year ago

fund count last 6Q
+27 new funds entered over the past year (+22% YoY). That's a rapid rush of institutional money. Fast accumulation often signals a major thesis — but it also means the stock could fall quickly if that thesis breaks.
🟡

Slight buying edge — 55% buying

83 buying69 selling
Last quarter: 83 funds bought or added vs 69 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.
📈

More new buyers each quarter (+11 vs last Q)

new funds entering per quarter
Funds opening a new LXRX position: 21 → 19 → 33 → 44. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
🔒

51% of holders stayed for 2+ years

■ 51% conviction (2yr+) ■ 22% medium ■ 28% new
75 out of 148 hedge funds have held LXRX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
💰

Value +73% but shares only +13% — price-driven

Value
+73%
Shares
+12%
Last quarter: the total dollar value of institutional holdings rose +73%, but actual share count only changed +13%. The gap is explained by the stock's price rising — not new buying. Strong value growth with weak share growth means the rally is price momentum, not fresh institutional demand.
🚀

Acceleration phase — new buyers rushing in

28 → 21 → 19 → 33 → 44 new funds/Q
New funds entering each quarter: 21 → 19 → 33 → 44. The pace of institutional discovery is accelerating sharply. This is the 'hot idea' phase — the thesis is being passed from fund to fund. You are not late — the accumulation wave is still building.
🏛️

Veteran-anchored — 58% veterans vs 31% newcomers

■ 58% veterans ■ 11% 1-2yr ■ 31% new
Entry-cohort mix of 152 holders: 88 (58%) are 2+ year veterans, 17 entered 1–2 years ago, and 47 (31%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
✅

Strong quality — 26% AUM from major funds

26% from top-100 AUM funds
40 of 147 holders rank in the top 100 by AUM, accounting for 26% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.
4.0
out of 10
Moderate Exit Risk
Exit risk score 4.0/10 — some crowding factors present, but no critical concentration. Watch ownership trend over the next 1–2 quarters for direction.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — LXRX

In 2026 Q2, 83 hedge funds were net buyers of LXRX (44 opened a new position, 39 added to an existing one), while 69 reduced or exited (37 trimmed, 32 sold completely) — a 55% buyer ratio, indicating a slight buying edge. Net buying has persisted for two consecutive quarters, a positive momentum signal. 26% of total institutional value in LXRX is held by top-100 AUM funds, reflecting strong institutional quality. Net fund flow last quarter: +12 funds (more new holders than closures). Total institutional holders: 148.

Hedge Fund Ownership: LXRX

How many hedge funds hold LXRX — quarterly history vs. share price
Quarterly hedge fund ownership of LXRX vs. share price

Market Analysis: LXRX

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: LXRX

-- --

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Is It Too Late to Buy Lexicon Pharmaceuticals Inc (LXRX) Based on Hedge Fund 13F Filings?

Signal Freshness measures how much LXRX has moved relative to its sector benchmark (XLV) since the 2026 Q2 13F filing. A stock that has barely outrun its sector is still a relatively fresh entry point — the fund's thesis has not yet been priced in by the broader market.

Since Quarter End June 30, 2026 · 54d ago
LXRX
-4.2%
XLV
+10.1%

LXRX outperformed XLV by -14.3% since June 30, 2026.

Since 13F Filing Date August 14, 2026 · 9d ago
LXRX
-0.9%
XLV
+4.3%

Since the filing became public, LXRX outperformed XLV by -5.2% .

Interpretation: The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference. Learn more →

Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

8 top-rated funds 2 high-conviction
Consensus
4.1
/ 10
breadth
×
Elite
1.6
/ 10
conviction
Hedge Fund Positioning: LXRX
147 + Investors

Track Smart Money conviction in LXRX. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q2) Prior (2026 Q1) Change
Funds Holding 147 136 8.09%
13F Shares 366M 325M 12.61%
Total Value $875M $505M 73.21%
New Positions 44 33 +11
Increased Positions 37 39 -2
Closed Positions 32 17 +15
Reduced Positions 36 28 +8
Total Calls 3 3 -
Total Puts 2 3 -33.33%
PUT/CALL Ratio 0.67 1.0 Bullish

Statistics: LXRX

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Valuation Measures Data as of: --

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Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

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Total Cash (mrq) --
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Institutional Holders (2026 Q2)

147 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in LXRX. Verified SEC 13F-HR filings.

QUARTER:
Top 25 LXRX holders by conviction (% of portfolio weight) — 2026 Q2 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Artal Group S.A. 45.15% 175,156,062 $420.4M
2 Ishara Investments LP 2.24% 1,271,000 $3.1M
3 Siren, L.L.C. 2.15% 44,303,518 $106.3M
4 Sessa Capital IM, L.P. 0.76% 18,960,836 $45.5M
5 Virtus Investment Advisers, LLC 0.10% 170,415 $409K
6 ADAR1 Capital Management, LLC 0.08% 750,000 $1.8M
7 R Squared Ltd 0.07% 54,985 $132K
8 Ikarian Capital, LLC 0.04% 164,674 $395K
9 Headlands Technologies LLC 0.04% 167,198 $401K
10 Diker Management LLC 0.04% 20,000 $48K
11 Straight Path Wealth Management 0.04% 62,666 $150K
12 Quarry LP 0.03% 156,186 $375K
13 Aster Capital Management (DIFC) Ltd 0.03% 130,452 $123K
14 State of Wyoming 0.03% 119,090 $286K
15 Invera Wealth Advisors, LLC 0.03% 20,000 $48K
16 Point72 Asset Management, L.P. 0.02% 8,251,325 $19.8M
17 University of Texas/Texas AM Investment Management Co 0.02% 71,427 $171K
18 Fortis Group Advisors, LLC 0.02% 50,000 $120K
19 Two Sigma Securities, LLC 0.01% 66,375 $159K
20 Compagnie Lombard Odier SCmA 0.01% 480,000 $1.2M
21 Axq Capital, LP 0.01% 45,727 $110K
22 XTX Topco Ltd 0.01% 357,877 $859K
23 Cornerstone Investment Partners, LLC 0.01% 113,739 $273K
24 Fmr LLC 0.01% 51,782,045 $124.3M
25 Renaissance Technologies LLC 0.00% 1,127,000 $2.7M
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Lexicon Pharmaceuticals Inc (LXRX)

What does the Smart Money Trend signal show for LXRX?

Buying streak — 2 quarters in a row: For 2 consecutive quarters, more hedge funds added LXRX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for LXRX?

Slight buying edge — 55% buying: Last quarter: 83 funds bought or added vs 69 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

What is the fund quality score for LXRX holders?

Strong quality — 26% AUM from major funds: 40 of 147 holders rank in the top 100 by AUM, accounting for 26% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.

How long have hedge funds held LXRX?

51% of holders stayed for 2+ years: 75 out of 148 hedge funds have held LXRX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Is it too late to buy Lexicon Pharmaceuticals Inc (LXRX) following the 2026 Q2 hedge fund 13F filings?

As of today, LXRX has moved -0.9% since the 2026 Q2 13F filing date (August 14, 2026), compared to +4.3% for the XLV sector ETF — an outperformance of -5.2%. Since the quarter end (June 30, 2026), LXRX has gained -4.2% vs +10.1% for XLV. The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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