Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

PROTAGONIST THERAPEUTICS INC (PTGX)

314 + Investors. Track Smart Money conviction in PTGX. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +43
Streak
1Q ▲
Buyers last Q
55%

Smart Money Signals — PTGX

Based on 302 hedge funds · latest filing: 2025 Q4 · updated quarterly

📈

Buying streak — 1 quarter in a row

last 6Q
For 1 consecutive quarter, more hedge funds added PTGX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
302 hedge funds hold PTGX right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
🚀

Fast accumulation — +33% more funds vs a year ago

fund count last 6Q
+75 new funds entered over the past year (+33% YoY). That's a rapid rush of institutional money. Fast accumulation often signals a major thesis — but it also means the stock could fall quickly if that thesis breaks.
🟡

Slight buying edge — 55% buying

175 buying141 selling
Last quarter: 175 funds bought or added vs 141 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.
📈

More new buyers each quarter (+40 vs last Q)

new funds entering per quarter
Funds opening a new PTGX position: 67 → 53 → 42 → 82. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
🔒

40% of holders stayed for 2+ years

■ 40% conviction (2yr+) ■ 29% medium ■ 30% new
121 out of 302 hedge funds have held PTGX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
💰

Value +32% but shares only +1% — price-driven

Value
+32%
Shares
+1%
Last quarter: the total dollar value of institutional holdings rose +32%, but actual share count only changed +1%. The gap is explained by the stock's price rising — not new buying. Strong value growth with weak share growth means the rally is price momentum, not fresh institutional demand.
➡️

Steady discovery — ~82 new funds/quarter

45 → 67 → 53 → 42 → 82 new funds/Q
New funds entering each quarter: 67 → 53 → 42 → 82. Consistent flow of new institutional buyers without clear acceleration or slowdown.
🏛️

Deep conviction — 49% of holders stayed 2+ years

■ 49% veterans ■ 16% 1-2yr ■ 35% new
Of 314 current holders: 154 (49%) have held for over 2 years without selling. These are not momentum buyers — they have lived through drawdowns and stayed. A large veteran base acts as a stabilizing force during selloffs.
🏆

Elite ownership — 40% AUM from top-100 funds

40% from top-100 AUM funds
40 of 302 holders are among the 100 largest funds by AUM, controlling 40% of total institutional value in PTGX. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.
4.0
out of 10
Moderate Exit Risk
Exit risk score 4.0/10 — some crowding factors present, but no critical concentration. Watch ownership trend over the next 1–2 quarters for direction.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — PTGX

In 2025 Q4, 175 hedge funds were net buyers of PTGX (82 opened a new position, 93 added to an existing one), while 141 reduced or exited (102 trimmed, 39 sold completely) — a 55% buyer ratio, indicating a slight buying edge. 40% of total institutional value in PTGX is held by top-100 AUM funds, reflecting elite-tier ownership quality. Net fund flow last quarter: +43 funds (more new holders than closures). Total institutional holders: 302.

Hedge Fund Ownership: PTGX

How many hedge funds hold PTGX — quarterly history vs. share price
Quarterly hedge fund ownership of PTGX vs. share price

Market Analysis: PTGX

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: PTGX

Healthcare Biotechnology

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Smart Money Signal ?
Broad Consensus, Selective Conviction

Many quality funds hold this stock, but top-tier positions remain relatively small.

50 top-rated funds 6 high-conviction
Consensus
7.4
/ 10
breadth
×
Elite
3.5
/ 10
conviction
Hedge Fund Positioning: PTGX
2026 Q1 Stats Unlock in 8 days 314 + Investors

Track Smart Money conviction in PTGX. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2025 Q4) Prior (2025 Q3) Change
Funds Holding 314 265 18.49%
13F Shares 71M 71M 1.0%
Total Value $6.11B $4.61B 32.46%
New Positions 87 42 +45
Increased Positions 104 89 +15
Closed Positions 39 45 -6
Reduced Positions 110 117 -7
Total Calls 13 5 160.0%
Total Puts 5 2 150.0%
PUT/CALL Ratio 0.38 0.4 Bullish

Statistics: PTGX

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Valuation Measures Data as of: --

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PEG Ratio (5yr expected) --
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Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

Profitability
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Income Statement & Cash Flow
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Total Cash (mrq) --
Total Debt/Equity (mrq) --
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Institutional Holders (2026 Q1)

314 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in PTGX. Verified SEC 13F-HR filings.

Top 25 institutional holders of PTGX — 2025 Q4 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 NAN FUNG TRINITY (HK) Ltd 1.86% 160,670 $16.9M
2 MOODY ALDRICH PARTNERS LLC 1.02% 53,893 $5.7M
3 AlphaCentric Advisors LLC 0.95% 9,040 $953K
4 HUSSMAN STRATEGIC ADVISORS, INC. 0.24% 10,500 $1.1M
5 PSP Research LLC 0.22% 3,000 $316K
6 Cache Advisors, LLC 0.12% 10,143 $1.1M
7 TFB Advisors LLC 0.12% 2,191 $231K
8 China Universal Asset Management Co., Ltd. 0.12% 14,923 $1.6M
9 SEB Asset Management AB 0.10% 232,416 $24.5M
10 Abel Hall, LLC 0.10% 4,258 $449K
11 PROFUND ADVISORS LLC 0.09% 22,867 $2.4M
12 UBS Group AG 0.08% 5,177,796 $545.7M
13 JENNISON ASSOCIATES LLC 0.08% 1,072,011 $113.0M
14 FRANKLIN STREET ADVISORS INC /NC 0.07% 11,085 $1.2M
15 Pictet Asset Management Holding SA 0.06% 581,083 $61.2M
16 Covestor Ltd 0.06% 875 —
17 King Wealth Management Group 0.05% 4,000 —
18 Louisiana State Employees Retirement System 0.05% 26,100 $3K
19 CFG Wealth Management Services, Inc. 0.05% 602 $53K
20 Inspire Investing, LLC 0.04% 5,036 $531K
21 State of Alaska, Department of Revenue 0.04% 37,147 $4K
22 Abacus Wealth Partners, LLC 0.04% 4,094 $432K
23 Illinois Municipal Retirement Fund 0.04% 28,596 $3.0M
24 Pinnacle Wealth Planning Services, Inc. 0.03% 3,132 $330K
25 NORDEN GROUP LLC 0.03% 2,810 $296K
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — PROTAGONIST THERAPEUTICS INC (PTGX)

What does the Smart Money Trend signal show for PTGX?

Buying streak — 1 quarter in a row: For 1 consecutive quarter, more hedge funds added PTGX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for PTGX?

Slight buying edge — 55% buying: Last quarter: 175 funds bought or added vs 141 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

What is the fund quality score for PTGX holders?

Elite ownership — 40% AUM from top-100 funds: 40 of 302 holders are among the 100 largest funds by AUM, controlling 40% of total institutional value in PTGX. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

How long have hedge funds held PTGX?

40% of holders stayed for 2+ years: 121 out of 302 hedge funds have held PTGX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.