Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Sionna Therapeutics Inc (SION)

144 + Investors. Track Smart Money conviction in SION. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +30
Streak
6Q ▲
Buyers last Q
67%

Smart Money Signals — SION

Based on 149 hedge funds · latest filing: 2026 Q2 · updated quarterly

📈

Buying streak — 6 quarters in a row

last 6Q
For 6 consecutive quarters, more hedge funds added SION than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
149 hedge funds hold SION right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
🚀

Fast accumulation — +129% more funds vs a year ago

fund count last 6Q
+84 new funds entered over the past year (+129% YoY). That's a rapid rush of institutional money. Fast accumulation often signals a major thesis — but it also means the stock could fall quickly if that thesis breaks.
🟢

More buyers than sellers — 67% buying

96 buying48 selling
Last quarter: 96 funds were net buyers (39 opened a brand new position + 57 added to an existing one). Only 48 were sellers (39 trimmed + 9 sold completely). A clear majority buying is a strong confirmation signal.
📈

More new buyers each quarter (+8 vs last Q)

new funds entering per quarter
Funds opening a new SION position: 19 → 30 → 31 → 39. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
🔄

Mostly new holders — 54% entered in last year

■ 3% conviction (2yr+) ■ 44% medium ■ 54% new
Only 4 funds (3%) have held >2 years. The majority of current holders are relatively new to the position. New holders tend to sell faster when prices drop — a shallow conviction base that could amplify any sell-off.
📈

Growing discovery — still being found

26 → 19 → 30 → 31 → 39 new funds/Q
New funds entering each quarter: 19 → 30 → 31 → 39. A growing number of institutions are discovering SION each quarter. The narrative is still spreading — leaving room for ongoing capital accumulation.
🌱

Early stage — 70% of holders entered in last year

■ 5% veterans ■ 25% 1-2yr ■ 70% new
Of 153 current holders: 107 (70%) entered in the past year, only 8 (5%) are 2+ year veterans. This is an early-phase institutional idea — still being discovered. High upside potential if the thesis plays out, but thin conviction base.
✅

Strong quality — 20% AUM from major funds

20% from top-100 AUM funds
38 of 145 holders rank in the top 100 by AUM, accounting for 20% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.
5.7
out of 10
Moderate Exit Risk
Exit risk score 5.7/10 — some crowding factors present, but no critical concentration. Watch ownership trend over the next 1–2 quarters for direction.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — SION

In 2026 Q2, 96 hedge funds were net buyers of SION (39 opened a new position, 57 added to an existing one), while 48 reduced or exited (39 trimmed, 9 sold completely) — a 67% buyer ratio, indicating clear institutional accumulation. This marks 6 consecutive quarters of net institutional buying — a persistent conviction signal. 20% of total institutional value in SION is held by top-100 AUM funds, reflecting strong institutional quality. Net fund flow last quarter: +30 funds (more new holders than closures). Total institutional holders: 149.

Hedge Fund Ownership: SION

How many hedge funds hold SION — quarterly history vs. share price
Quarterly hedge fund ownership of SION vs. share price

Market Analysis: SION

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: SION

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Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

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Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

10 top-rated funds 4 high-conviction
Consensus
4.5
/ 10
breadth
×
Elite
3.5
/ 10
conviction
Hedge Fund Positioning: SION
144 + Investors

Track Smart Money conviction in SION. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q2) Prior (2026 Q1) Change
Funds Holding 144 119 21.01%
13F Shares 48M 44M 9.87%
Total Value $2.10B $1.73B 21.13%
New Positions 39 31 +8
Increased Positions 56 38 +18
Closed Positions 10 12 -2
Reduced Positions 38 30 +8
Total Calls 3 0 100%
Total Puts 5 0 100%
PUT/CALL Ratio 1.67 0.0 Bearish

Statistics: SION

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Institutional Holders (2026 Q2)

144 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in SION. Verified SEC 13F-HR filings.

QUARTER:
Top 25 SION holders by conviction (% of portfolio weight) — 2026 Q2 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Enavate Sciences GP, LLC 31.56% 2,478,030 $109.0M
2 Atlas Venture Life Science Advisors, LLC 14.95% 2,995,602 $131.8M
3 Kalehua Capital Management LLC 6.21% 197,072 $8.7M
4 Tpg GP A, LLC 5.71% 6,494,962 $285.7M
5 Ra Capital Management, L.P. 3.79% 9,905,045 $435.7M
6 GordonMD Global Investments LP 2.89% 136,000 $6.0M
7 Orbimed Advisors LLC 2.08% 2,555,877 $112.4M
8 Superstring Capital Management LP 1.75% 63,156 $2.8M
9 Artia Global Partners LP 0.97% 119,741 $5.3M
10 Sio Capital Management, LLC 0.93% 127,808 $5.6M
11 Casdin Capital, LLC 0.88% 400,000 $17.6M
12 Perceptive Advisors LLC 0.60% 905,000 $39.8M
13 Siren, L.L.C. 0.54% 610,515 $26.9M
14 First Turn Management, LLC 0.52% 110,493 $4.9M
15 Ikarian Capital, LLC 0.51% 107,500 $4.7M
16 Stempoint Capital LP 0.45% 59,426 $2.6M
17 Rhenman & Partners Asset Management AB 0.40% 97,100 $4.3M
18 Viking Global Investors LP 0.40% 3,195,181 $140.6M
19 Sofinnova Investments, Inc. 0.33% 144,432 $6.4M
20 Deerfield Management Company, L.P. 0.31% 680,916 $30.0M
21 Eventide Asset Management, LLC 0.28% 474,981 $20.9M
22 Soleus Capital Management, L.P. 0.27% 177,687 $7.8M
23 Rock Springs Capital Management LP 0.21% 99,429 $4.4M
24 Silverarc Capital Management, LLC 0.19% 42,478 $1.9M
25 Longaeva Partners L.P. 0.19% 196,352 $8.6M
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Sionna Therapeutics Inc (SION)

What does the Smart Money Trend signal show for SION?

Buying streak — 6 quarters in a row: For 6 consecutive quarters, more hedge funds added SION than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for SION?

More buyers than sellers — 67% buying: Last quarter: 96 funds were net buyers (39 opened a brand new position + 57 added to an existing one). Only 48 were sellers (39 trimmed + 9 sold completely). A clear majority buying is a strong confirmation signal.

What is the fund quality score for SION holders?

Strong quality — 20% AUM from major funds: 38 of 145 holders rank in the top 100 by AUM, accounting for 20% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.

How long have hedge funds held SION?

Mostly new holders — 54% entered in last year: Only 4 funds (3%) have held >2 years. The majority of current holders are relatively new to the position. New holders tend to sell faster when prices drop — a shallow conviction base that could amplify any sell-off.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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