Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

TYRA BIOSCIENCES INC COM (TYRA)

130 + Investors. Track Smart Money conviction in TYRA. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +18
Streak
1Q ▲
Buyers last Q
60%

Smart Money Signals — TYRA

Based on 130 hedge funds · latest filing: 2025 Q4 · updated quarterly

📈

Buying streak — 1 quarter in a row

last 6Q
For 1 consecutive quarter, more hedge funds added TYRA than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
130 hedge funds hold TYRA right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
📶

Steady growth — +20% more funds vs a year ago

fund count last 6Q
+22 new funds entered over the past year (+20% YoY). Gradual, steady growth in institutional ownership is generally a healthy signal — not a speculative rush, but consistent conviction.
🟢

More buyers than sellers — 60% buying

72 buying48 selling
Last quarter: 72 funds were net buyers (29 opened a brand new position + 43 added to an existing one). Only 48 were sellers (37 trimmed + 11 sold completely). A clear majority buying is a strong confirmation signal.
📈

More new buyers each quarter (+21 vs last Q)

new funds entering per quarter
Funds opening a new TYRA position: 22 → 18 → 8 → 29. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
📌

Mixed — 36% long-term, 30% new

■ 36% conviction (2yr+) ■ 34% medium ■ 30% new
Of the 130 current holders: 47 (36%) held >2 years, 44 held 1–2 years, and 39 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.
💰

Value +94% but shares only +3% — price-driven

Value
+93%
Shares
+3%
Last quarter: the total dollar value of institutional holdings rose +94%, but actual share count only changed +3%. The gap is explained by the stock's price rising — not new buying. Strong value growth with weak share growth means the rally is price momentum, not fresh institutional demand.
➡️

Steady discovery — ~29 new funds/quarter

31 → 22 → 18 → 8 → 29 new funds/Q
New funds entering each quarter: 22 → 18 → 8 → 29. Consistent flow of new institutional buyers without clear acceleration or slowdown.
📊

Mixed cohorts — 38% veterans, 46% new entrants

■ 38% veterans ■ 16% 1-2yr ■ 46% new
Of 130 current holders: 49 (38%) held 2+ years, 21 held 1–2 years, 60 (46%) entered in the past year. Balanced distribution — some institutional memory, some recent momentum buyers.
📋

Smaller funds dominant — 14% AUM from top-100

14% from top-100 AUM funds
29 of 130 holders rank in the top 100 by AUM, but together hold only 14% of total institutional value. The stock is held primarily by smaller and mid-sized funds.
3.9
out of 10
Low Exit Risk
Exit risk score 3.9/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Hedge Fund Ownership: TYRA

How many hedge funds hold TYRA — quarterly history vs. share price
Quarterly hedge fund ownership of TYRA vs. share price

Market Analysis: TYRA

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: TYRA

-- --

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

27 top-rated funds 8 high-conviction
Consensus
6.3
/ 10
breadth
×
Elite
3.5
/ 10
conviction
Hedge Fund Positioning: TYRA
2026 Q1 Stats Unlock in 10 days 130 + Investors

Track Smart Money conviction in TYRA. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2025 Q4) Prior (2025 Q3) Change
Funds Holding 130 113 15.04%
13F Shares 53M 51M 3.05%
Total Value $1.39B $720M 93.62%
New Positions 29 8 +21
Increased Positions 43 38 +5
Closed Positions 11 15 -4
Reduced Positions 38 39 -1
Total Calls 1 1 -
Total Puts 0 0 -
PUT/CALL Ratio 0.0 0.0 Bullish

Statistics: TYRA

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Valuation Measures Data as of: --

Market Cap --
Enterprise Value --
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Forward P/E --
PEG Ratio (5yr expected) --
Price/Sales (ttm) --
Price/Book (mrq) --
Enterprise Value/Revenue --
Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

Profitability
Profit Margin --
Return on Assets (ttm) --
Return on Equity (ttm) --
Income Statement & Cash Flow
Revenue (ttm) --
Net Income Avi to Common (ttm) --
Diluted EPS (ttm) --
Total Cash (mrq) --
Total Debt/Equity (mrq) --
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Institutional Holders (2026 Q1)

130 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in TYRA. Verified SEC 13F-HR filings.

Top 25 institutional holders of TYRA — 2025 Q4 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Alta Partners Management Company, L.P. 96.97% 3,823,425 $146.4M
2 Canaan Partners XI LLC 37.76% 750,000 $28.7M
3 PSP Research LLC 0.43% 16,000 $613K
4 Auour Investments LLC 0.25% 21,020 $805K
5 OPPENHEIMER & CO INC 0.04% 84,192 $3.2M
6 China Universal Asset Management Co., Ltd. 0.03% 9,471 $363K
7 PROFUND ADVISORS LLC 0.02% 15,656 $600K
8 Hilton Head Capital Partners, LLC 0.02% 772 $30K
9 JENNISON ASSOCIATES LLC 0.02% 632,432 $24.2M
10 ALPS ADVISORS INC 0.01% 43,856 $1.7M
11 AlphaQuest LLC 0.00% 2,139 $56K
12 Versant Capital Management, Inc 0.00% 819 $31K
13 Russell Investments Group, Ltd. 0.00% 70,422 $2.7M
14 STRS OHIO 0.00% 18,100 $693K
15 INTECH INVESTMENT MANAGEMENT LLC 0.00% 6,345 $243K
16 Police & Firemen's Retirement System of New Jersey 0.00% 6,440 $247K
17 VANGUARD FIDUCIARY TRUST CO 0.00% 157,791 $6.0M
18 True Wealth Design, LLC 0.00% 142 $5K
19 VANGUARD CAPITAL MANAGEMENT LLC 0.00% 1,125,970 $43.1M
20 GAMMA Investing LLC 0.00% 506 $19K
21 GF FUND MANAGEMENT CO. LTD. 0.00% 1,198 $46K
22 Sterling Capital Management LLC 0.00% 858 $33K
23 Swiss National Bank 0.00% 26,400 $1.0M
24 VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% 247,270 $9.5M
25 KLP KAPITALFORVALTNING AS 0.00% 2,900 $111K
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — TYRA BIOSCIENCES INC COM (TYRA)

What does the Smart Money Trend signal show for TYRA?

Buying streak — 1 quarter in a row: For 1 consecutive quarter, more hedge funds added TYRA than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for TYRA?

More buyers than sellers — 60% buying: Last quarter: 72 funds were net buyers (29 opened a brand new position + 43 added to an existing one). Only 48 were sellers (37 trimmed + 11 sold completely). A clear majority buying is a strong confirmation signal.

What is the fund quality score for TYRA holders?

Smaller funds dominant — 14% AUM from top-100: 29 of 130 holders rank in the top 100 by AUM, but together hold only 14% of total institutional value. The stock is held primarily by smaller and mid-sized funds.

How long have hedge funds held TYRA?

Mixed — 36% long-term, 30% new: Of the 130 current holders: 47 (36%) held >2 years, 44 held 1–2 years, and 39 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.