MPM BioImpact LLC — 13F Holdings

2026 Q2  ·  48 Positions

2026 Q2 Portfolio Activity

In 2026 Q2, MPM BioImpact LLC maintained a portfolio of 48 distinct positions. The most significant new addition was Ultragenyx Pharmaceuticals, In, now representing 2.89% of the total fund value. They heavily accumulated shares in Cullinan Therapeutics, Inc., increasing the position by 27.2%. The fund also reduced its exposure to DBV Technologies S A by 29.7%.
Position History hover any row below to update
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MPM BioImpact LLC Boston, MA Venture Capital / Life Sciences Specialist AUM $1,640M
PCA Score Concentration Risk
Risk ENB
Total Positions
48
Quarter
2026 Q2
Top Holding
CGEM (10.8%)
Top 10 Concentration
55.3%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
Showing 1-48 of 48

MPM BioImpact LLC Full Holdings List — 2026 Q2

Stock History Sector / Type Port % Prev % Rank / Prev Conviction
Freshness
Change % Change Influence Shares Mkt Value Avg Cost Price Held 1st Owned Source Source Date Date Reported
CGEM
Cullinan Therap...
Healthcare 10.81% 8.39% #1 1
Prev: #2
8.5
2,083,073 27.2%
P
S
9,731,341 $177,207,720 2021 Q1 13F Filing 2026-06-30 2026-08-14
N/A
Aktis Oncology,...
Unknown 9.50% 6.68% #2 1
Prev: #3
6.3
no change no change
P
S
4,835,872 $155,860,155 13F Filing 2026-06-30 2026-08-14
LQDA
Liquidia Corpor...
Healthcare 6.74% 4.10% #3 1
Prev: #4
4.2
-18,984 -1.4%
P
S
1,386,174 $110,519,653 2025 Q3 13F Filing 2026-06-30 2026-08-14
RVMD
Revolution Medi...
Healthcare 5.62% 3.81% #4 3
Prev: #7
3.2
-14,293 -2.8%
P
S
492,483 $92,232,216 2021 Q3 13F Filing 2026-06-30 2026-08-14
CORT
Corcept Therape...
Healthcare 4.09% 3.07% #5 4
Prev: #9
2.1
-214,672 -21.8%
P
S
771,028 $67,040,885 2026 Q1 13F Filing 2026-06-30 2026-08-14
EWTX
Edgewise Therap...
Healthcare 4.02% 4.04% #6
Prev: #6
2.1
-39,916 -2.4%
P
S
1,620,780 $65,852,291 2022 Q3 13F Filing 2026-06-30 2026-08-14
TVTX
Travere Therape...
Healthcare 3.89% 2.60% #7 7
Prev: #14
2.1
-10,634 -0.9%
P
S
1,122,731 $63,782,348 2021 Q3 13F Filing 2026-06-30 2026-08-14
DBVT
DBV Technologie...
Healthcare 3.67% 8.41% #8 7
Prev: #1
1.5
-1,547,077 -29.7%
P
S
3,666,284 $60,127,058 2025 Q2 13F Filing 2026-06-30 2026-08-14
TRVI
Trevi Therapeut...
Healthcare 3.50% 3.04% #9 1
Prev: #10
1.9
-224,853 -6.8%
P
S
3,073,577 $57,322,211 2024 Q1 13F Filing 2026-06-30 2026-08-14
ALMS
Alumis Inc
Healthcare 3.46% 4.06% #10 5
Prev: #5
1.9
-367,509 -15.4%
P
S
2,019,020 $56,815,223 2025 Q4 13F Filing 2026-06-30 2026-08-14
QURE
Uniqure NV
Healthcare 3.44% 1.73% #11 16
Prev: #27
1.9
-143,376 -10.5%
P
S
1,225,855 $56,462,881 2022 Q4 13F Filing 2026-06-30 2026-08-14
RARE
Ultragenyx Phar...
Healthcare 2.89% #12
Prev: #—
4.7
1,418,215
NEW
1,418,215 $47,354,199 2024 Q1 13F Filing 2026-06-30 2026-08-14
RLAY
Relay Therapeut...
Healthcare 2.76% 1.81% #13 11
Prev: #24
1.6
56,086 2.4%
P
S
2,415,672 $45,197,223 2023 Q1 13F Filing 2026-06-30 2026-08-14
ABVX
Abivax SA
Healthcare 2.73% 0.92% #14 24
Prev: #38
4.1
229,079 213.6%
P
S
336,347 $44,821,601 2025 Q4 13F Filing 2026-06-30 2026-08-14
DYN
Dyne Therapeuti...
Healthcare 2.60% 1.97% #15 6
Prev: #21
3.5
513,941 36.5%
P
S
1,922,093 $42,689,686 2025 Q2 13F Filing 2026-06-30 2026-08-14
DNTH
Dianthus Therap...
Healthcare 2.50% 2.75% #16 5
Prev: #11
1.5
-3,980 -0.9%
P
S
420,002 $40,941,795 2026 Q1 13F Filing 2026-06-30 2026-08-14
BIOA
BIOAGE Labs Inc
Healthcare 2.49% #17
Prev: #—
4.5
1,667,661
NEW
1,667,661 $40,874,371 2026 Q2 13F Filing 2026-06-30 2026-08-14
URGN
Urogen Pharma L...
Healthcare 2.09% 1.31% #18 14
Prev: #32
1.3
-10,388 -1.1%
P
S
933,415 $34,349,672 2025 Q3 13F Filing 2026-06-30 2026-08-14
MLTX
MoonLake Immuno...
Healthcare 1.91% 2.61% #19 6
Prev: #13
1.3
-204,115 -11.3%
P
S
1,606,967 $31,287,647 2023 Q2 13F Filing 2026-06-30 2026-08-14
PVLA
Palvella Therap...
Healthcare 1.90% 1.99% #20
Prev: #20
1.3
-2,377 -1.2%
P
S
204,027 $31,179,406 2025 Q3 13F Filing 2026-06-30 2026-08-14
TSHA
Taysha Gene The...
Healthcare 1.87% #21
Prev: #—
4.2
4,500,000
NEW
4,500,000 $30,645,000 2025 Q2 13F Filing 2026-06-30 2026-08-14
SNDX
Syndax Pharmace...
Healthcare 1.78% 2.42% #22 5
Prev: #17
1.2
-7,210 -0.5%
P
S
1,333,523 $29,150,813 2025 Q3 13F Filing 2026-06-30 2026-08-14
GLUE
Monte Rosa Ther...
Healthcare 1.71% 1.50% #23 5
Prev: #28
1.2
-15,847 -1.3%
P
S
1,161,081 $28,098,160 2025 Q4 13F Filing 2026-06-30 2026-08-14
ZURA
Zura Bio Ltd.
Healthcare 1.61% #24
Prev: #—
4.1
4,472,843
NEW
4,472,843 $26,389,774 2026 Q2 13F Filing 2026-06-30 2026-08-14
NTRA
Natera Inc
Healthcare 1.53% 1.44% #25 4
Prev: #29
1.1
-436 -0.5%
P
S
92,638 $25,146,585 2024 Q1 13F Filing 2026-06-30 2026-08-14
STOK
Stoke Therapeut...
Healthcare 1.44% 1.93% #26 4
Prev: #22
1.1
-43,724 -5.7%
P
S
723,314 $23,666,834 2024 Q3 13F Filing 2026-06-30 2026-08-14
ANL
Adlai Nortye Lt...
Healthcare 1.36% #27
Prev: #—
4.0
1,936,291
NEW
1,936,291 $22,267,347 2026 Q2 13F Filing 2026-06-30 2026-08-14
BLTE
Belite Bio Inc
Healthcare 1.29% 1.08% #28 7
Prev: #35
3.5
49,163 55.8%
P
S
137,208 $21,127,974 2025 Q4 13F Filing 2026-06-30 2026-08-14
FBRX
Forte Bioscienc...
Healthcare 1.28% 2.00% #29 10
Prev: #19
1.0
-13,234 -1.3%
P
S
987,448 $20,983,270 2026 Q1 13F Filing 2026-06-30 2026-08-14
ORIC
Oric Pharmaceut...
Healthcare 1.24% 1.77% #30 4
Prev: #26
1.0
78,217 4.3%
P
S
1,882,162 $20,383,814 2025 Q1 13F Filing 2026-06-30 2026-08-14
TARS
Tarsus Pharmace...
Healthcare 1.24% 1.79% #31 6
Prev: #25
1.0
-7,743 -2.3%
P
S
322,007 $20,267,121 2025 Q2 13F Filing 2026-06-30 2026-08-14
ANNX
Annexon Inc
Healthcare 1.23% #32
Prev: #—
4.0
3,544,354
NEW
3,544,354 $20,238,261 2026 Q2 13F Filing 2026-06-30 2026-08-14
DRUG
Bright Minds Bi...
Healthcare 0.87% 1.20% #33
Prev: #33
0.8
-10,061 -4.7%
P
S
202,114 $14,188,403 2025 Q4 13F Filing 2026-06-30 2026-08-14
TRDA
Entrada Therape...
Healthcare 0.56% #34
Prev: #—
3.7
1,253,053
NEW
1,253,053 $9,222,470 2026 Q2 13F Filing 2026-06-30 2026-08-14
ACRS
Aclaris Therape...
Healthcare 0.34% 0.11% #35 5
Prev: #40
3.1
650,549 166.0%
P
S
1,042,467 $5,514,650 2026 Q1 13F Filing 2026-06-30 2026-08-14
CNTX
Context Therape...
Healthcare 0.04% 2.16% #36 18
Prev: #18
0.0
-9,380,345 -87.8%
P
S
1,299,046 $719,542 2024 Q4 13F Filing 2026-06-30 2026-08-14
HOWL
Werewolf Therap...
Healthcare 0.00% 0.08% #37 4
Prev: #41
0.0
-1,128,668 -93.4%
P
S
80,142 $28,851 2021 Q2 13F Filing 2026-06-30 2026-08-14
ALLO
Allogene Therap...
Healthcare 0.00% 0.42%
Sold All 😨
(Was: #39)
0.0
-2,242,933 -100.0%
CLOSED
$— 2026 Q1 13F Filing 2026-06-30 2026-08-14
ENGN
enGene Holdings...
Healthcare 0.00% 0.97%
Sold All 😨
(Was: #37)
0.0
-1,845,373 -100.0%
CLOSED
$— 2025 Q3 13F Filing 2026-06-30 2026-08-14
VRDN
Viridian Therap...
Healthcare 0.00% 0.98%
Sold All 😨
(Was: #36)
0.0
-649,873 -100.0%
CLOSED
$— 2023 Q2 13F Filing 2026-06-30 2026-08-14
ZYME
Zymeworks, Inc.
Healthcare 0.00% 1.09%
Sold All 😨
(Was: #34)
0.0
-565,249 -100.0%
CLOSED
$— 2026 Q1 13F Filing 2026-06-30 2026-08-14
ARQT
Arcutis Biother...
Healthcare 0.00% 1.34%
Sold All 😨
(Was: #31)
0.0
-733,966 -100.0%
CLOSED
$— 2022 Q1 13F Filing 2026-06-30 2026-08-14
CLYM
Climb Bio Inc
Healthcare 0.00% 1.37%
Sold All 😨
(Was: #30)
0.0
-2,593,439 -100.0%
CLOSED
$— 2025 Q4 13F Filing 2026-06-30 2026-08-14
CRVS
Corvus Pharmace...
Healthcare 0.00% 1.89%
Sold All 😨
(Was: #23)
0.0
-1,674,875 -100.0%
CLOSED
$— 2025 Q4 13F Filing 2026-06-30 2026-08-14
CYTK
Cytokinetics In...
Healthcare 0.00% 2.54%
Sold All 😨
(Was: #16)
0.0
-500,000 -100.0%
CLOSED
$— 2021 Q3 13F Filing 2026-06-30 2026-08-14
EVMN
Evommune Inc
Healthcare 0.00% 2.58%
Sold All 😨
(Was: #15)
0.0
-1,455,863 -100.0%
CLOSED
$— 2025 Q4 13F Filing 2026-06-30 2026-08-14
XENE
Xenon Pharmaceu...
Healthcare 0.00% 2.64%
Sold All 😨
(Was: #12)
0.0
-588,706 -100.0%
CLOSED
$— 2024 Q3 13F Filing 2026-06-30 2026-08-14
AGIO
Agios Pharmaceu...
Healthcare 0.00% 3.41%
Sold All 😨
(Was: #8)
0.0
-1,306,261 -100.0%
CLOSED
$— 2025 Q4 13F Filing 2026-06-30 2026-08-14
Showing 1-48 of 48 holdings

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